منابع مشابه
Folate and human reproduction.
The influence of folate nutritional status on various pregnancy outcomes has long been recognized. Studies conducted in the 1950s and 1960s led to the recognition of prenatal folic acid supplementation as a means to prevent pregnancy-induced megaloblastic anemia. In the 1990s, the utility of periconceptional folic acid supplementation and folic acid food fortification emerged when they were pro...
متن کاملQuantitation of in vivo human folate metabolism.
BACKGROUND A quantitative understanding of human folate metabolism is needed. OBJECTIVE The objective was to quantify and interpret human folate metabolism as it might occur in vivo. DESIGN Adults (n = 13) received 0.5 nmol [(14)C]pteroylmonoglutamate (100 nCi radioactivity) plus 79.5 nmol pteroylmonoglutamate in water orally. (14)C was measured in plasma, erythrocytes, urine, and feces for...
متن کاملFolate Metabolism and Preeclampsia
1OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada. 2Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa, Ontario, Canada. 3School of Public Health, Central South University, Changsha, Hunan, PRC. 4Huaihua Medical College, Huaihua, Hunan, PRC. 5Queen’s Perinatal Research Unit, Department of Obst...
متن کاملImpact of folate and homocysteine metabolism on human reproductive health.
Folates belong to the vitamin B group and are involved in a large number of biochemical processes, particularly in the metabolism of homocysteine. Dietary or genetically determined folate deficiency leads to mild hyperhomocysteinemia, which has been associated with various pathologies. Molecular mechanisms of homocysteine-induced cellular dysfunction include increased inflammatory cytokine expr...
متن کاملOral contraceptives and folate metabolism.
1. There are conflicting reports regarding the effect of oral contraceptives on serum and erythrocyte folate concentrations and on folate absorption. A detailed study of this problem was therefore undertaken. 2. It was first ascertained that there was no significant variation in serum folate concentrations at different stages in the normal menstrual cycle. 3. No significant difference was found...
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ژورنال
عنوان ژورنال: Geburtshilfe und Frauenheilkunde
سال: 2014
ISSN: 0016-5751,1438-8804
DOI: 10.1055/s-0034-1383058